The IQD Family of Calmodulin-Binding Proteins Links Calcium Signaling to Microtubules, Membrane Subdomains, and the Nucleus1[OPEN]
نویسندگان
چکیده
Department of Molecular Signal Processing, Leibniz Institute of Plant Biochemistry, 06120 Halle (Saale), Germany (K.B., R.P., G.S., D.M., S.A.); Institute of Computer Science (B.M.), Biocenter (G.H.), and Institute of Biochemistry and Biotechnology (S.A.), Martin Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany; and Department of Plant Sciences, University of California, Davis, California 95616 (S.A.)
منابع مشابه
The IQD Family of Calmodulin-Binding Proteins Links Calcium Signaling to Microtubules, Membrane Subdomains, and the Nucleus.
Calcium (Ca2+) signaling and dynamic reorganization of the cytoskeleton are essential processes for the coordination and control of plant cell shape and cell growth. Calmodulin (CaM) and closely related calmodulin-like (CML) polypeptides are principal sensors of Ca2+ signals. CaM/CMLs decode and relay information encrypted by the second messenger via differential interactions with a wide spectr...
متن کاملFunctions of IQD proteins as hubs in cellular calcium and auxin signaling: A toolbox for shape formation and tissue-specification in plants?
Calcium (Ca2+) ions play pivotal roles as second messengers in intracellular signal transduction, and coordinate many biological processes. Changes in intracellular Ca2+ levels are perceived by Ca2+ sensors such as calmodulin (CaM) and CaM-like (CML) proteins, which transduce Ca2+ signals into cellular responses by regulation of diverse target proteins. Insights into molecular functions of CaM ...
متن کاملCrystal structure of kinesin regulated by Ca/calmodulin
Kinesins orchestrate cell division by controlling placement of chromosomes. Kinesins must be precisely regulated or else cell division fails. Calcium, a universal second messenger in eukaryotes, and calmodulin regulate some kinesins by causing the motor to dissociate from its biological track, the microtubule. Our focus was the mechanism of calcium regulation of kinesin at atomic resolution. He...
متن کاملThe cytoskeletal system of nucleated erythrocytes. II. presence of a high molecular weight calmodulin-binding protein
Calmodulin was detected in dogfish erythrocyte lysates by means of phosphodiesterase activation. Anucleate dogfish erythrocyte cytoskeletons bound calmodulin. Binding of calmodulin was calcium-dependent, concentration-dependent, and saturable. Cytoskeletons consisted of a marginal band of microtubules containing primarily tubulin, and trans-marginal band material containing actin and spectrinli...
متن کاملCapital Cells: The American Society for Cell Biology, Washington, D.C., December 1–5, 2007
JCB • VOLUME 180 • NUMBER 4 • 2008 654 STIM1 (green) hooks the ER to microtubule plus ends (red). A KH M A N O VA / EL SE VI ER ER takes trip on microtubule tips T he ER membrane hitches a ride on the tips of microtubules, as revealed by Susana Montenegro Gouveia. Gouveia, Ilya Grigoriev, and Anna Akhmanova (Erasmus Medical Center, Rotterdam, Netherlands) are interested in the growing tips of m...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2017